Guanidine hydrochloride
Orukọ ọja: Guanidine Hydrochloride
Aminoformamidine hydrochloride tabi Guanidinium kiloraidi
Irisi: funfun tabi odidi ofeefee.
Data ohun-ini ti ara
1. Ti ohun kikọ silẹ: funfun tabi odidi ofeefee
2. Ibi yo (℃): 181-183
3. iwuwo ibatan (g / milimita, 20/4 ℃): 1.354
4. Solubility: 228g ni omi 100g, 76g ni methanol 100g ati 24g ni 100g ethanol ni 20 ℃. O fẹrẹ jẹ insoluble ninu acetone, benzene ati ether.
5. Iye PH (4% ojutu olomi, 25 ℃): 6.4
Awọn ohun-ini ati iduroṣinṣin
Ọja yii jẹ riru ati pe a le ṣe hydrolyzed sinu amonia ati urea ni ojutu olomi, nitorina majele rẹ jẹ kanna bii ti urea. Guanidine ati awọn itọsẹ rẹ ni gbogbogbo majele ju urea lọ.
Idi: 1. O le ṣee lo bi agbedemeji ti oogun, ipakokoropaeku, awọ ati isopọ eleto miiran. O le ṣee lo lati ṣapọpọ 2-Aminopyrimidine, 2-amino-6-methylpyrimidine ati 2-amino-4,6-dimethylpyrimidine. O jẹ agbedemeji fun iṣelọpọ ti sulfadiazine, sulfamethylpyrimidine ati sulfadimidine.
2. Guanidine hydrochloride (tabi iyọ guanidine) ṣe atunṣe pẹlu ethyl cyanoacetate lati ṣe agbekalẹ 2,4-diamino-6-hydroxypyrimidine, eyiti o lo lati ṣapọpọ egboogi ẹjẹ folic acid. O tun le ṣee lo bi oluranlowo antistatic fun awọn okun sintetiki.
3. O tun le ṣee lo bi denaturant amuaradagba.
- Gẹgẹbi denaturant ti o lagbara ninu idanwo ti yiyo lapapọ RNA. Ojutu Guanidine hydrochloride le tu amuaradagba, fa ibajẹ eto sẹẹli, ibajẹ elekeji amuaradagba iparun, pin kuro lati acid nucleic, ni afikun, RNase le jẹ alaisise nipasẹ idinku oluranlowo bii guanidine hydrochloride.
sintetiki ọna
Lilo dicyandiamide ati iyọ ammonium (ammonium kiloraidi) bi awọn ohun elo aise, a ti gba guanidine hydrochloride ti ko ni nkan nipasẹ didi iyọ ni 170-230 ℃, ati pe ọja ti o pari ni a gba nipasẹ isọdọtun.
Iṣakoso olubasọrọ
1. Maṣe simi eruku
2. Ipalara ti o ba gbeemi
3. Irunu oju
4. Irunu ara
Idaabobo ti ara ẹni
1. Wọ aṣọ aabo lati yago fun taarata taara tabi ifasimu; 2. Maṣe mu, jẹ tabi mu siga ni iṣẹ; 3. Lo awọn gilaasi aabo